From UCSF Medical Center:
Healthy older subjects in the study could easily distinguish sincere from insincere speech. However, the subjects who had frontotemporal dementia were less able to discern among lies, sarcasm, and fact. Patients with other forms of dementia, such as Alzheimer's disease, did better. To associate the detection inability with neurodegeneration, the UCSF team used MRI to make extremely accurate maps of the brains of the subjects in the study. This allowed them to measure the volumes of different regions of the brain showing that the sizes of those regions correlated with the inability to detect sarcasm or lying.
According to Rankin, the work should help raise awareness of the fact that this extreme form of gullibility can actually be a warning sign of dementia -- something that could help more patients be correctly diagnosed and receive treatment earlier in the long run.
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